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[ESH2010]肾素抑制剂心血管保护作用机制及糖尿病合并高血压患者降压策略——Bryan Williams教授采访
Interview with Dr. Bryan Williams
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作者:B.Williams 编辑:国际循环网 时间:2010/6/19 10:48:00    加入收藏
 关键字:肾素抑制剂 高血压 糖尿病 Navigator B.Williams 

    《国际循环》:“选择最佳联合是科学而不是艺术”的发言是非常好的优秀的演讲。您能否用两三句话简单总结一下为个体患者选择何种联合策略?

     <International Circulation>:The speech on “Choosing the optimal combination is a science, not an art” is a very nice and excellent presentation. Could you just conclude what the strategy is for choosing a combination for individual patients in two or three sentences?

    Williams教授:我认为,我说的第一点是因为大多数卒中激活肾素-血管紧张素系统,因此肾素-血管紧张素系统阻滞应是联合治疗的一部分。目前,我认为血管紧张素受体阻断剂是耐受更好的肾素-血管紧张素系统阻滞剂,因此我会在联合策略中包括这种药物。然后,我们可以选择利尿剂或CCB,我认为对多数患者来说,CCB是优选的联合,因其不良反应较少,且治疗问题较少。但一些患者会需要利尿剂,如果他们有水肿的话。   

    Prof. Williams: I think the first point that I made was that because most strokes activate the renin-angiotensin system, and the renin-angiotensin system blockade has to be part of the combination of treatment. I think at the moment, the angiotensin receptor blockers are the better tolerated blockers of the renin-angiotensin system, so I would include those in a combination. And then we have the option of either diuretic or CCB, and I think for most people, a CCB is a preferred combination because it has less side effects and less problems with treatment. But some people will need diuretic if they have edema.



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